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Identification of brain-enriched proteins in the cerebrospinal fluid proteome by LC-MS/MS profiling and mining of the Human Protein Atlas

BACKGROUND: Cerebrospinal fluid (CSF) is a proximal fluid which communicates closely with brain tissue, contains numerous brain-derived proteins and thus represents a promising fluid for discovery of biomarkers of central nervous system (CNS) diseases. The main purpose of this study was to generate...

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Detalles Bibliográficos
Autores principales: Begcevic, Ilijana, Brinc, Davor, Drabovich, Andrei P., Batruch, Ihor, Diamandis, Eleftherios P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868024/
https://www.ncbi.nlm.nih.gov/pubmed/27186164
http://dx.doi.org/10.1186/s12014-016-9111-3