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Combinatorial Genetic Modeling of pfcrt-Mediated Drug Resistance Evolution in Plasmodium falciparum

The emergence of drug resistance continuously threatens global control of infectious diseases, including malaria caused by the protozoan parasite Plasmodium falciparum. A critical parasite determinant is the P. falciparum chloroquine resistance transporter (PfCRT), the primary mediator of chloroquin...

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Detalles Bibliográficos
Autores principales:	Gabryszewski, Stanislaw J., Modchang, Charin, Musset, Lise, Chookajorn, Thanat, Fidock, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Discoveries
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868112/ https://www.ncbi.nlm.nih.gov/pubmed/26908582 http://dx.doi.org/10.1093/molbev/msw037

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