Cargando…
Purifying Selection on Exonic Splice Enhancers in Intronless Genes
Exonic splice enhancers (ESEs) are short nucleotide motifs, enriched near exon ends, that enhance the recognition of the splice site and thus promote splicing. Are intronless genes under selection to avoid these motifs so as not to attract the splicing machinery to an mRNA that should not be spliced...
Autores principales: | Savisaar, Rosina, Hurst, Laurence D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868121/ https://www.ncbi.nlm.nih.gov/pubmed/26802218 http://dx.doi.org/10.1093/molbev/msw018 |
Ejemplares similares
-
Exonic splice regulation imposes strong selection at synonymous sites
por: Savisaar, Rosina, et al.
Publicado: (2018) -
Both Maintenance and Avoidance of RNA-Binding Protein Interactions Constrain Coding Sequence Evolution
por: Savisaar, Rosina, et al.
Publicado: (2017) -
Estimating the prevalence of functional exonic splice regulatory information
por: Savisaar, Rosina, et al.
Publicado: (2017) -
Purifying Selection on Splice-Related Motifs, Not Expression Level nor RNA Folding, Explains Nearly All Constraint on Human lincRNAs
por: Schüler, Andreas, et al.
Publicado: (2014) -
Why Selection Might Be Stronger When Populations Are Small: Intron Size and Density Predict within and between-Species Usage of Exonic Splice Associated cis-Motifs
por: Wu, XianMing, et al.
Publicado: (2015)