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Testing for Hardy–Weinberg equilibrium at biallelic genetic markers on the X chromosome
Testing genetic markers for Hardy–Weinberg equilibrium (HWE) is an important tool for detecting genotyping errors in large-scale genotyping studies. For markers at the X chromosome, typically the χ(2) or exact test is applied to the females only, and the hemizygous males are considered to be uninfor...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868269/ https://www.ncbi.nlm.nih.gov/pubmed/27071844 http://dx.doi.org/10.1038/hdy.2016.20 |