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Interaction of Atmospheric-Pressure Air Microplasmas with Amino Acids as Fundamental Processes in Aqueous Solution

Plasma medicine is a relatively new field that investigates potential applications of cold atmospheric-pressure plasmas in bioengineering, such as for bacterial inactivation and degradation of organic molecules in water. In order to enunciate mechanisms of bacterial inactivation at molecular or atom...

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Autores principales: Zhou, Renwu, Zhou, Rusen, Zhuang, Jinxing, Zong, Zichao, Zhang, Xianhui, Liu, Dongping, Bazaka, Kateryna, Ostrikov, Kostya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868320/
https://www.ncbi.nlm.nih.gov/pubmed/27183129
http://dx.doi.org/10.1371/journal.pone.0155584
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author Zhou, Renwu
Zhou, Rusen
Zhuang, Jinxing
Zong, Zichao
Zhang, Xianhui
Liu, Dongping
Bazaka, Kateryna
Ostrikov, Kostya
author_facet Zhou, Renwu
Zhou, Rusen
Zhuang, Jinxing
Zong, Zichao
Zhang, Xianhui
Liu, Dongping
Bazaka, Kateryna
Ostrikov, Kostya
author_sort Zhou, Renwu
collection PubMed
description Plasma medicine is a relatively new field that investigates potential applications of cold atmospheric-pressure plasmas in bioengineering, such as for bacterial inactivation and degradation of organic molecules in water. In order to enunciate mechanisms of bacterial inactivation at molecular or atomic levels, we investigated the interaction of atmospheric-pressure air microplasmas with amino acids in aqueous solution by using high-resolution mass spectrometry (HRMS). Results show that the oxidation effect of plasma-induced species on the side chains of the amino acids can be categorized into four types, namely hydroxylation, nitration, dehydrogenation and dimerization. In addition, relative activities of amino acids resulting from plasma treatment come in descending order as follows: sulfur-containing carbon-chain amino acids > aromatic amino acids > five-membered ring amino acids > basic carbon-chain amino acids. Since amino acids are building blocks of proteins vital to the growth and reproduction of bacteria, these results provide an insight into the mechanism of bacterial inactivation by plasma.
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spelling pubmed-48683202016-05-26 Interaction of Atmospheric-Pressure Air Microplasmas with Amino Acids as Fundamental Processes in Aqueous Solution Zhou, Renwu Zhou, Rusen Zhuang, Jinxing Zong, Zichao Zhang, Xianhui Liu, Dongping Bazaka, Kateryna Ostrikov, Kostya PLoS One Research Article Plasma medicine is a relatively new field that investigates potential applications of cold atmospheric-pressure plasmas in bioengineering, such as for bacterial inactivation and degradation of organic molecules in water. In order to enunciate mechanisms of bacterial inactivation at molecular or atomic levels, we investigated the interaction of atmospheric-pressure air microplasmas with amino acids in aqueous solution by using high-resolution mass spectrometry (HRMS). Results show that the oxidation effect of plasma-induced species on the side chains of the amino acids can be categorized into four types, namely hydroxylation, nitration, dehydrogenation and dimerization. In addition, relative activities of amino acids resulting from plasma treatment come in descending order as follows: sulfur-containing carbon-chain amino acids > aromatic amino acids > five-membered ring amino acids > basic carbon-chain amino acids. Since amino acids are building blocks of proteins vital to the growth and reproduction of bacteria, these results provide an insight into the mechanism of bacterial inactivation by plasma. Public Library of Science 2016-05-16 /pmc/articles/PMC4868320/ /pubmed/27183129 http://dx.doi.org/10.1371/journal.pone.0155584 Text en © 2016 Zhou et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Zhou, Renwu
Zhou, Rusen
Zhuang, Jinxing
Zong, Zichao
Zhang, Xianhui
Liu, Dongping
Bazaka, Kateryna
Ostrikov, Kostya
Interaction of Atmospheric-Pressure Air Microplasmas with Amino Acids as Fundamental Processes in Aqueous Solution
title Interaction of Atmospheric-Pressure Air Microplasmas with Amino Acids as Fundamental Processes in Aqueous Solution
title_full Interaction of Atmospheric-Pressure Air Microplasmas with Amino Acids as Fundamental Processes in Aqueous Solution
title_fullStr Interaction of Atmospheric-Pressure Air Microplasmas with Amino Acids as Fundamental Processes in Aqueous Solution
title_full_unstemmed Interaction of Atmospheric-Pressure Air Microplasmas with Amino Acids as Fundamental Processes in Aqueous Solution
title_short Interaction of Atmospheric-Pressure Air Microplasmas with Amino Acids as Fundamental Processes in Aqueous Solution
title_sort interaction of atmospheric-pressure air microplasmas with amino acids as fundamental processes in aqueous solution
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868320/
https://www.ncbi.nlm.nih.gov/pubmed/27183129
http://dx.doi.org/10.1371/journal.pone.0155584
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