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Rethinking Dosing Regimen Selection of Piperaquine for Malaria Chemoprevention: A Simulation Study

BACKGROUND: The combination of short-acting dihydroartemisinin and long-acting piperaquine (DP) is among the first-line therapies for the treatment of uncomplicated Plasmodium falciparum malaria. Population pharmacokinetic models of piperaquine (PQ) based on data from acute treatment of young childr...

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Detalles Bibliográficos
Autores principales:	Sambol, Nancy C., Tappero, Jordan W., Arinaitwe, Emmanuel, Parikh, Sunil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868321/ https://www.ncbi.nlm.nih.gov/pubmed/27182702 http://dx.doi.org/10.1371/journal.pone.0154623

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