Rapid Acquisition of Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus: Role of Hypermutation and Homologous Recombination

BACKGROUND: We previously reported the case of a 64-year-old man with mediastinitis caused by Staphylococcus aureus in which the infecting bacterium acquired linezolid resistance after only 14 days treatment with linezolid. We therefore investigated relevant clinical isolates for possible mechanisms...

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Detalles Bibliográficos
Autores principales: Iguchi, Shigekazu, Mizutani, Tomonori, Hiramatsu, Keiichi, Kikuchi, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868352/
https://www.ncbi.nlm.nih.gov/pubmed/27182700
http://dx.doi.org/10.1371/journal.pone.0155512

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