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RNA polymerase errors cause splicing defects and can be regulated by differential expression of RNA polymerase subunits

Errors during transcription may play an important role in determining cellular phenotypes: the RNA polymerase error rate is >4 orders of magnitude higher than that of DNA polymerase and errors are amplified >1000-fold due to translation. However, current methods to measure RNA polymerase fidel...

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Detalles Bibliográficos
Autor principal:	Carey, Lucas B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868539/ https://www.ncbi.nlm.nih.gov/pubmed/26652005 http://dx.doi.org/10.7554/eLife.09945

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