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Mcl-1 dynamics influence mitotic slippage and death in mitosis

Microtubule-binding drugs such as taxol are frontline treatments for a variety of cancers but exactly how they yield patient benefit is unclear. In cell culture, inhibiting microtubule dynamics prevents spindle assembly, leading to mitotic arrest followed by either apoptosis in mitosis or slippage,...

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Detalles Bibliográficos
Autores principales:	Sloss, Olivia, Topham, Caroline, Diez, Maria, Taylor, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Chromosome
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868679/ https://www.ncbi.nlm.nih.gov/pubmed/26769847 http://dx.doi.org/10.18632/oncotarget.6894

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