Cargando…

Rab23 promotes squamous cell carcinoma cell migration and invasion via integrin β1/Rac1 pathway

Rab23 was a member of Ras-related small GTPase family, which played a key role in the regulation of Shh signaling pathway. However, the function and regulatory mechanism of Rab23 in cutaneous squamous cell carcinoma was unknown. In this study, we found that the expression level of Rab23 was higher i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jian, Qiang, Miao, Ye, Tang, Li, Huang, Min, Yang, Yi, Ba, Wei, Liu, Yali, Chi, Sumin, Li, Chengxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868690/ https://www.ncbi.nlm.nih.gov/pubmed/26716504 http://dx.doi.org/10.18632/oncotarget.6701

Ejemplares similares

A novel caveolin-1/p85α/Rab5/Tiam1/Rac1 signaling axis in tumor cell migration and invasion
por: Díaz, Jorge, et al.
Publicado: (2014)

Identification of potential gene drivers of cutaneous squamous cell carcinoma: Analysis of microarray data
por: Zheng, Yi, et al.
Publicado: (2020)

The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy
por: Carroll, Bernadette, et al.
Publicado: (2013)

Integrin-mediated Signaling via Paxillin-GIT1-PIX Promotes Localized Rac Activation at the Leading Edge and Cell Migration
por: Li, Youjun, et al.
Publicado: (2020)

Hydrogen Sulfide Recruits Macrophage Migration by Integrin β1-Src-FAK/Pyk2-Rac Pathway in Myocardial Infarction
por: Miao, Lei, et al.
Publicado: (2016)

Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K
por: Yamaguchi, Naoya, et al.
Publicado: (2015)

The NKD1/Rac1 feedback loop regulates the invasion and migration ability of hepatocarcinoma cells
por: Li, Jie, et al.
Publicado: (2016)

The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling
por: Sandri, Chiara, et al.
Publicado: (2012)

Rac1-PAK1 regulation of Rab11 cycling promotes junction destabilization
por: Erasmus, Jennifer C., et al.
Publicado: (2021)

The Rho-Family GTPase Rac1 Regulates Integrin Localization in Drosophila Immunosurveillance Cells
por: Xavier, Miguel J., et al.
Publicado: (2011)

Rab-coupling protein coordinates recycling of α5β1 integrin and EGFR1 to promote cell migration in 3D microenvironments
por: Caswell, Patrick T., et al.
Publicado: (2008)

Coordination between Rac1 and Rab Proteins: Functional Implications in Health and Disease
por: Margiotta, Azzurra, et al.
Publicado: (2019)

Rab proteins move integrins
por: Tuma, Rabiya S.
Publicado: (2006)

SUMOylation of the GTPase Rac1 is required for optimal cell migration
por: Castillo-Lluva, Sonia, et al.
Publicado: (2010)

The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation
por: Borza, Corina M., et al.
Publicado: (2022)

Author Correction: Hydrogen Sulfide Recruits Macrophage Migration by Integrin β1-Src-FAK/Pyk2-Rac Pathway in Myocardial Infarction
por: Miao, Lei, et al.
Publicado: (2022)

Rab23’s genetic structure, function and related diseases: a review
por: Zheng, Li-Qiang, et al.
Publicado: (2017)

Two Rac1 pools integrate the direction and coordination of collective cell migration
por: Zhou, Sijia, et al.
Publicado: (2022)

Nm23-H1 suppresses hepatocarcinoma cell adhesion and migration on fibronectin by modulating glycosylation of integrin beta1
por: She, Shangyang, et al.
Publicado: (2010)

Transmembrane Collagen XVII Modulates Integrin Dependent Keratinocyte Migration via PI3K/Rac1 Signaling
por: Löffek, Stefanie, et al.
Publicado: (2014)

Microrna 130b Suppresses Migration and Invasion of Colorectal Cancer Cells through Downregulation of Integrin β1
por: Zhao, Yanyang, et al.
Publicado: (2014)

Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division
por: Petracchini, Serena, et al.
Publicado: (2022)

Rac1 and Rac3 GTPases Regulate the Development of Hilar Mossy Cells by Affecting the Migration of Their Precursors to the Hilus
por: Pennucci, Roberta, et al.
Publicado: (2011)

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration
por: Marei, Hadir, et al.
Publicado: (2016)

Distinct predictive performance of Rac1 and Cdc42 in cell migration
por: Yamao, Masataka, et al.
Publicado: (2015)

Distinctive roles of Rac1 and Rab29 in LRRK2 mediated membrane trafficking and neurite outgrowth
por: Feng, Min, et al.
Publicado: (2018)

HUWE1 Ubiquitylates and Degrades the RAC Activator TIAM1 Promoting Cell-Cell Adhesion Disassembly, Migration, and Invasion
por: Vaughan, Lynsey, et al.
Publicado: (2014)

Integrin-Rac signalling for mammary epithelial stem cell self-renewal
por: Olabi, Safiah, et al.
Publicado: (2018)

Silencing of integrin subunit α3 inhibits the proliferation, invasion, migration and autophagy of esophageal squamous cell carcinoma cells
por: Du, Jin, et al.
Publicado: (2022)

Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer
por: Peng, Chaozhong, et al.
Publicado: (2021)

The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation, and cell migration
por: Saxena, Madhurima, et al.
Publicado: (2013)

Hax-1 is required for Rac1-Cortactin interaction and ovarian carcinoma cell migration
por: Gomathinayagam, Rohini, et al.
Publicado: (2014)

Ankyrin–Tiam1 Interaction Promotes Rac1 Signaling and Metastatic Breast Tumor Cell Invasion and Migration
por: Bourguignon, Lilly Y.W., et al.
Publicado: (2000)

RAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation
por: Karthikeyan, Subbulakshmi, et al.
Publicado: (2022)

TGF-β-Dependent Growth Arrest and Cell Migration in Benign and Malignant Breast Epithelial Cells Are Antagonistically Controlled by Rac1 and Rac1b
por: Melzer, Catharina, et al.
Publicado: (2017)

Rab5 Isoforms Orchestrate a “Division of Labor” in the Endocytic Network; Rab5C Modulates Rac-Mediated Cell Motility
por: Chen, Pin-I, et al.
Publicado: (2014)

Knockdown of RAC1 and VASP gene expression inhibits breast cancer cell migration
por: Tian, Yihao, et al.
Publicado: (2018)

β1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination
por: Nodari, Alessandro, et al.
Publicado: (2007)

Rab25 regulates integrin expression in polarized colonic epithelial cells
por: Krishnan, Moorthy, et al.
Publicado: (2013)

Rac Activation by the T-Cell Receptor Inhibits T Cell Migration
por: Cernuda-Morollón, Eva, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_tjc97k2th6dmhdom462rphhhk6