Cargando…

The identification of two regulatory ESCC susceptibility genetic variants in the TERT-CLPTM1L loci

The chromosome 5p15.33 TERT-CLPTM1L region has been identified by genome-wide association studies as a susceptibility locus of multiple malignancies. However, the involvement of this locus in esophageal squamous cell carcinoma (ESCC) development is still largely unclear. We fine-mapped the TERT-CLPT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Liqing, Fu, Guobin, Wei, Jinyu, Shi, Juan, Pan, Wenting, Ren, Yanli, Xiong, Xiangyu, Xia, Jianhong, Shen, Yue, Li, Hongliang, Yang, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868701/ https://www.ncbi.nlm.nih.gov/pubmed/26716642 http://dx.doi.org/10.18632/oncotarget.6747

Ejemplares similares

Functional evaluation of TERT-CLPTM1L genetic variants associated with susceptibility of papillary thyroid carcinoma
por: Ge, Minghua, et al.
Publicado: (2016)

The Sp1-mediaded allelic regulation of MMP13 expression by an ESCC susceptibility SNP rs2252070
por: Shi, Meng, et al.
Publicado: (2016)

Genetic polymorphisms in the TERT-CLPTM1L region and lung cancer susceptibility in Chinese males
por: Xiao, Xuyang, et al.
Publicado: (2017)

TERT-CLPTM1 locus polymorphism (rs401681) is associated with the prognosis of hepatocellular carcinoma
por: Lee, Hye Won, et al.
Publicado: (2017)

Genetic Variations in TERT-CLPTM1L Genes and Risk of Lung Cancer in Chinese Women Nonsmokers
por: Li, Cheng, et al.
Publicado: (2013)

Genetic variations in the TERT and CLPTM1L gene region and gastrointestinal stromal tumors risk
por: Zhang, Rui, et al.
Publicado: (2015)

Cumulative Evidence for Relationships Between Multiple Variants in the TERT and CLPTM1L Region and Risk of Cancer and Non-Cancer Disease
por: Tian, Jie, et al.
Publicado: (2022)

Rs401681 polymorphism in TERT-CLPTM1L was associated with bladder cancer risk: A meta-analysis
por: Zhang, Meng, et al.
Publicado: (2015)

Common variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populations
por: Zhang, Yang, et al.
Publicado: (2015)

Combined detection of peripheral blood VEGF and inflammation biomarkers to evaluate the clinical response and prognostic prediction of non-operative ESCC
por: Ma, Yuanyuan, et al.
Publicado: (2021)

Meta-analysis combining new and existing data sets confirms that the TERT-CLPTM1L locus influences melanoma risk
por: Law, Matthew H., et al.
Publicado: (2011)

A Regulatory MDM4 Genetic Variant Locating in the Binding Sequence of Multiple MicroRNAs Contributes to Susceptibility of Small Cell Lung Cancer
por: Gao, Feng, et al.
Publicado: (2015)

HPV seropositivity joints with susceptibility loci identified in GWASs at apoptosis associated genes to increase the risk of Esophageal Squamous Cell Carcinoma (ESCC)
por: Yang, Ju, et al.
Publicado: (2014)

Functional BCL-2 regulatory genetic variants contribute to susceptibility of esophageal squamous cell carcinoma
por: Pan, Wenting, et al.
Publicado: (2015)

TERT-CLPTM1L Rs401681 C>T Polymorphism Was Associated with a Decreased Risk of Esophageal Cancer in a Chinese Population
por: Yin, Jun, et al.
Publicado: (2014)

Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk
por: Carvajal-Carmona, Luis G., et al.
Publicado: (2014)

Erratum: Functional BCL-2 regulatory genetic variants contribute to susceptibility of esophageal squamous cell carcinoma
por: Pan, Wenting, et al.
Publicado: (2015)

Replication Study of ESCC Susceptibility Genetic Polymorphisms Locating in the ADH1B-ADH1C-ADH7 Cluster Identified by GWAS
por: Wang, Jiwen, et al.
Publicado: (2014)

TERT-CLPTM1L Polymorphism rs401681 Contributes to Cancers Risk: Evidence from a Meta-Analysis Based on 29 Publications
por: Yin, Jieyun, et al.
Publicado: (2012)

CLPTM1L Is Overexpressed in Lung Cancer and Associated with Apoptosis
por: Ni, Zhenhua, et al.
Publicado: (2012)

Absence of association of a single-nucleotide polymorphism in the TERT-CLPTM1L locus with age-related phenotypes in a large multicohort study: the HALCyon programme
por: Alfred, Tamuno, et al.
Publicado: (2011)

An Immune Cell-Based Signature Associating With EMT Phenotype Predicts Postoperative Overall Survival of ESCC
por: Yu, Hongliang, et al.
Publicado: (2021)

A GWAS in uveal melanoma identifies risk polymorphisms in the CLPTM1L locus
por: Mobuchon, Lenha, et al.
Publicado: (2017)

UBE2C is overexpressed in ESCC tissues and its abrogation attenuates the malignant phenotype of ESCC cell lines
por: Palumbo, Antonio, et al.
Publicado: (2016)

Functional Screenings Identify Regulatory Variants Associated with Breast Cancer Susceptibility
por: Ren, Naixia, et al.
Publicado: (2021)

Longer Telomere Length in Peripheral White Blood Cells Is Associated with Risk of Lung Cancer and the rs2736100 (CLPTM1L-TERT) Polymorphism in a Prospective Cohort Study among Women in China
por: Lan, Qing, et al.
Publicado: (2013)

Functional Annotation of Putative Regulatory Elements at Cancer Susceptibility Loci
por: Rosse, Stephanie A, et al.
Publicado: (2014)

Assessing a single SNP located at TERT/CLPTM1L multi-cancer risk region as a genetic modifier for risk of pancreatic cancer and melanoma in Dutch CDKN2A mutation carriers
por: Christodoulou, E., et al.
Publicado: (2019)

Prognosis and Progression of ESCC Patients with Perineural Invasion
por: Xu, Guanghui, et al.
Publicado: (2017)

CLPTM1L Is a Novel Putative Oncogene Promoting Tumorigenesis in Oral Squamous Cell Carcinoma
por: Hou, Yunwen, et al.
Publicado: (2021)

MEX3A is upregulated in esophageal squamous cell carcinoma (ESCC) and promotes development and progression of ESCC through targeting CDK6
por: Wei, Lei, et al.
Publicado: (2020)

Enrichment of Cis-Regulatory Gene Expression SNPs and Methylation Quantitative Trait Loci Among Bipolar Disorder Susceptibility Variants
por: Gamazon, ER, et al.
Publicado: (2012)

Reply: Hookah, opium, and tobacco smoking in relation to ESCC
por: Malekzadeh, R, et al.
Publicado: (2009)

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma
por: Went, Molly, et al.
Publicado: (2018)

Combination of Clptm1L and TMEM207 Expression as a Robust Prognostic Marker in Oral Squamous Cell Carcinoma
por: Hano, Kimika, et al.
Publicado: (2021)

Genome-wide CRISPR screen reveals CLPTM1L as a lipid scramblase required for efficient glycosylphosphatidylinositol biosynthesis
por: Wang, Yicheng, et al.
Publicado: (2022)

CCGD-ESCC: A Comprehensive Database for Genetic Variants Associated with Esophageal Squamous Cell Carcinoma in Chinese Population
por: Peng, Linna, et al.
Publicado: (2018)

Identification and Validation of Potential Pathogenic Genes and Prognostic Markers in ESCC by Integrated Bioinformatics Analysis
por: Tang, Lu, et al.
Publicado: (2020)

SCARA5 induced ferroptosis to effect ESCC proliferation and metastasis by combining with Ferritin light chain
por: Liu, Yanqun, et al.
Publicado: (2022)

ATF3 suppresses ESCC via downregulation of ID1
por: Li, Jian, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_7n092t27brum4knng0qu7m2q4c