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N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins

Pseudomonas aeruginosa produces N-(3-oxododecanoyl)-homoserine lactone (C12) as a quorum-sensing molecule for bacterial communication. C12 has also been reported to induce apoptosis in various types of tumor cells. However, the detailed molecular mechanism of C12-triggerred tumor cell apoptosis is s...

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Detalles Bibliográficos
Autores principales:	Zhao, Guoping, Neely, Aaron M., Schwarzer, Christian, Lu, Huayi, Whitt, Aaron G., Stivers, Nicole S., Burlison, Joseph A., White, Carl, Machen, Terry E., Li, Chi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868731/ https://www.ncbi.nlm.nih.gov/pubmed/26758417 http://dx.doi.org/10.18632/oncotarget.6827

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