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Nucleosomal arrays self‐assemble into supramolecular globular structures lacking 30‐nm fibers

The existence of a 30‐nm fiber as a basic folding unit for DNA packaging has remained a topic of active discussion. Here, we characterize the supramolecular structures formed by reversible Mg(2+)‐dependent self‐association of linear 12‐mer nucleosomal arrays using microscopy and physicochemical appr...

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Detalles Bibliográficos
Autores principales: Maeshima, Kazuhiro, Rogge, Ryan, Tamura, Sachiko, Joti, Yasumasa, Hikima, Takaaki, Szerlong, Heather, Krause, Christine, Herman, Jake, Seidel, Erik, DeLuca, Jennifer, Ishikawa, Tetsuya, Hansen, Jeffrey C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868957/
https://www.ncbi.nlm.nih.gov/pubmed/27072995
http://dx.doi.org/10.15252/embj.201592660