Molecular determinants of plaque size as an indicator of dengue virus attenuation

The development of live viral vaccines relies on empirically derived phenotypic criteria, especially small plaque sizes, to indicate attenuation. However, while some candidate vaccines successfully translated into licensed applications, others have failed safety trials, placing vaccine development o...

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Detalles Bibliográficos
Autores principales: Goh, Kenneth Choon Meng, Tang, Choon Kit, Norton, Diana Catherine, Gan, Esther Shuyi, Tan, Hwee Cheng, Sun, Bo, Syenina, Ayesa, Yousuf, Amjad, Ong, Xin Mei, Kamaraj, Uma Sangumathi, Cheung, Yin Bun, Gubler, Duane J, Davidson, Andrew, St John, Ashley Lauren, Sessions, October Michael, Ooi, Eng Eong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868997/
https://www.ncbi.nlm.nih.gov/pubmed/27185466
http://dx.doi.org/10.1038/srep26100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868997/
https://www.ncbi.nlm.nih.gov/pubmed/27185466
http://dx.doi.org/10.1038/srep26100

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