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Mice with Dab1 or Vldlr insufficiency exhibit abnormal neonatal vocalization patterns

Genetic and epigenetic changes in components of the Reelin-signaling pathway (RELN, DAB1) are associated with autism spectrum disorder (ASD) risk. Social communication deficits are a key component of the ASD diagnostic criteria, but the underlying neurogenetic mechanisms remain unknown. Reln insuffi...

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Detalles Bibliográficos
Autores principales: Fraley, E. R., Burkett, Z. D., Day, N. F., Schwartz, B. A., Phelps, P. E., White, S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868998/
https://www.ncbi.nlm.nih.gov/pubmed/27184477
http://dx.doi.org/10.1038/srep25807