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Functional evaluation of TERT-CLPTM1L genetic variants associated with susceptibility of papillary thyroid carcinoma

TERT is the catalytic subunit of telomerase which plays an essential part in cellular immortality by maintaining telomere integrity. TERT is commonly over-expressed in human malignancies, indicating its key role in cell transformation. The chromosome 5p15.33 TERT-CLPTM1L region has been associated w...

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Detalles Bibliográficos
Autores principales:	Ge, Minghua, Shi, Meng, An, Changming, Yang, Wenjun, Nie, Xilin, Zhang, Jian, Lv, Zheng, Li, Jinliang, Zhou, Liqing, Du, Zhongli, Yang, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869017/ https://www.ncbi.nlm.nih.gov/pubmed/27185198 http://dx.doi.org/10.1038/srep26037

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