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Spatial organization of heterologous metabolic system in vivo based on TALE
For years, prokaryotic hosts have been widely applied in bio-engineering. However, the confined in vivo enzyme clustering of heterologous metabolic pathways in these organisms often results in low local concentrations of enzymes and substrates, leading to a low productive efficacy. We developed a ne...
Autores principales: | Zhu, Ling-yun, Qiu, Xin-yuan, Wu, Xiao-min, Zhang, Yuan, Zhu, Qian-hui, Fan, Dong-yu, Zhu, Chu-shu, Zhang, Dong-yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869064/ https://www.ncbi.nlm.nih.gov/pubmed/27184291 http://dx.doi.org/10.1038/srep26065 |
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