miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis

The ability of the unfolded protein response, UPR, to regulate cell homeostasis through both gene expression and protein synthesis has been well documented. One primary pro-apoptotic protein that responds to both PERK and Ire1 signalling is the CHOP/GADD153 transcription factor. Although CHOP defici...

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Detalles Bibliográficos
Autores principales: Xu, Zhenhua, Bu, Yiwen, Chitnis, Nilesh, Koumenis, Costas, Fuchs, Serge Y., Diehl, J. Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869177/
https://www.ncbi.nlm.nih.gov/pubmed/27173017
http://dx.doi.org/10.1038/ncomms11422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869177/
https://www.ncbi.nlm.nih.gov/pubmed/27173017
http://dx.doi.org/10.1038/ncomms11422

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