Coarse-grained simulation reveals key features of HIV-1 capsid self-assembly

The maturation of HIV-1 viral particles is essential for viral infectivity. During maturation, many copies of the capsid protein (CA) self-assemble into a capsid shell to enclose the viral RNA. The mechanistic details of the initiation and early stages of capsid assembly remain to be delineated. We...

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Detalles Bibliográficos
Autores principales: Grime, John M. A., Dama, James F., Ganser-Pornillos, Barbie K., Woodward, Cora L., Jensen, Grant J., Yeager, Mark, Voth, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869257/
https://www.ncbi.nlm.nih.gov/pubmed/27174390
http://dx.doi.org/10.1038/ncomms11568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869257/
https://www.ncbi.nlm.nih.gov/pubmed/27174390
http://dx.doi.org/10.1038/ncomms11568

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