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Can abscopal effects of local radiotherapy be predicted by modeling T cell trafficking?
The abscopal effect of radiation describes tumor regression in metastases outside of the field upon treatment of one site, and is mediated by radiation-induced anti-tumor T cells. The ability of radiation to generate an in situ tumor vaccine and improve responses to immunotherapy is under intense in...
Autores principales: | Demaria, Sandra, Formenti, Silvia C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869282/ https://www.ncbi.nlm.nih.gov/pubmed/27190630 http://dx.doi.org/10.1186/s40425-016-0133-1 |
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