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Variable RBE in proton therapy: comparison of different model predictions and their influence on clinical-like scenarios

BACKGROUND: In proton radiation therapy a constant relative biological effectiveness (RBE) of 1.1 is usually assumed. However, biological experiments have evidenced RBE dependencies on dose level, proton linear energy transfer (LET) and tissue type. This work compares the predictions of three of the...

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Detalles Bibliográficos
Autores principales: Giovannini, Giulia, Böhlen, Till, Cabal, Gonzalo, Bauer, Julia, Tessonnier, Thomas, Frey, Kathrin, Debus, Jürgen, Mairani, Andrea, Parodi, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869317/
https://www.ncbi.nlm.nih.gov/pubmed/27185038
http://dx.doi.org/10.1186/s13014-016-0642-6