Cargando…

Variable RBE in proton therapy: comparison of different model predictions and their influence on clinical-like scenarios

Mostrar otras versiones (1)

BACKGROUND: In proton radiation therapy a constant relative biological effectiveness (RBE) of 1.1 is usually assumed. However, biological experiments have evidenced RBE dependencies on dose level, proton linear energy transfer (LET) and tissue type. This work compares the predictions of three of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giovannini, Giulia, Böhlen, Till, Cabal, Gonzalo, Bauer, Julia, Tessonnier, Thomas, Frey, Kathrin, Debus, Jürgen, Mairani, Andrea, Parodi, Katia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869317/ https://www.ncbi.nlm.nih.gov/pubmed/27185038 http://dx.doi.org/10.1186/s13014-016-0642-6

Ejemplares similares

Variable RBE in proton therapy: comparison of different model predictions and their influence on clinical-like scenarios
por: Giovannini, Giulia, et al.
Publicado: (2016)

Biophysical modeling and experimental validation of relative biological effectiveness (RBE) for (4)He ion beam therapy
por: Mein, Stewart, et al.
Publicado: (2019)

Data-driven RBE parameterization for helium ion beams
por: Mairani, A, et al.
Publicado: (2016)

Impact of DNA Repair Kinetics and Dose Rate on RBE Predictions in the UNIVERSE
por: Liew, Hans, et al.
Publicado: (2022)

How can we consider variable RBE and LET(d) prediction during clinical practice? A pediatric case report at the Normandy Proton Therapy Centre using an independent dose engine
por: Mein, Stewart, et al.
Publicado: (2022)

Optimizing the modified microdosimetric kinetic model input parameters for proton and $^4$He ion beam therapy application
por: Mairani, A, et al.
Publicado: (2017)

Dosimetric verification in water of a Monte Carlo treatment planning tool for proton, helium, carbon and oxygen ion beams at the Heidelberg Ion Beam Therapy Center
por: Tessonnier, T, et al.
Publicado: (2017)

Proton and helium ion radiotherapy for meningioma tumors: a Monte Carlo-based treatment planning comparison
por: Tessonnier, Thomas, et al.
Publicado: (2018)

RBE predictions by the BIANCA model for $in$ $vitro$ and $in$ $vivo$ irradiations in hadron therapy scenarios
por: Carante, M P, et al.
Publicado: (2021)

Phase Space Generation for Proton and Carbon Ion Beams for External Users’ Applications at the Heidelberg Ion Therapy Center
por: Tessonnier, Thomas, et al.
Publicado: (2016)

A phenomenological relative biological effectiveness approach for proton therapy based on an improved description of the mixed radiation field
por: Mairani, A, et al.
Publicado: (2017)

Fixed- versus Variable-RBE Computations for Intensity Modulated Proton Therapy
por: Yepes, Pablo, et al.
Publicado: (2018)

Combined RBE and OER optimization in proton therapy with FLUKA based on EF5‐PET
por: Henjum, Helge, et al.
Publicado: (2023)

Next generation multi-scale biophysical characterization of high precision cancer particle radiotherapy using clinical proton, helium-, carbon- and oxygen ion beams
por: Dokic, Ivana, et al.
Publicado: (2016)

Next generation multi-scale biophysical characterization of high precision cancer particle radiotherapy using clinical proton, helium-, carbon- and oxygen ion beams
por: Dokic, Ivana, et al.
Publicado: (2016)

Dual‐layer spectral CT for proton, helium, and carbon ion beam therapy planning of brain tumors
por: Longarino, Friderike K., et al.
Publicado: (2021)

Quantifying Systematic RBE-Weighted Dose Uncertainty Arising from Multiple Variable RBE Models in Organ at Risk
por: Koh, Wei Yang Calvin, et al.
Publicado: (2021)

In Vivo Validation of the BIANCA Biophysical Model: Benchmarking against Rat Spinal Cord RBE Data
por: Carante, Mario P, et al.
Publicado: (2020)

In Vivo Validation of the BIANCA Biophysical Model: Benchmarking against Rat Spinal Cord RBE Data
por: Carante, Mario P., et al.
Publicado: (2020)

Radiobiological effects and proton RBE determined by wildtype zebrafish embryos
por: Szabó, Emília Rita, et al.
Publicado: (2018)

Helium ions at the heidelberg ion beam therapy center: comparisons between FLUKA Monte Carlo code predictions and dosimetric measurements
por: Tessonnier, T, et al.
Publicado: (2017)

RBE for deterministic effects
por: Commission Internationale de Protection contre les Radiations
Publicado: (1989)

Fast robust dose calculation on GPU for high-precision (1)H, (4)He, (12)C and (16)O ion therapy: the FRoG platform
por: Mein, Stewart, et al.
Publicado: (2018)

Influence of beam pruning techniques on LET and RBE in proton arc therapy
por: Henjum, Helge, et al.
Publicado: (2023)

The Impact of Sub-Millisecond Damage Fixation Kinetics on the In Vitro Sparing Effect at Ultra-High Dose Rate in UNIVERSE
por: Liew, Hans, et al.
Publicado: (2022)

Do We Preserve Tumor Control Probability (TCP) in FLASH Radiotherapy? A Model-Based Analysis
por: Liew, Hans, et al.
Publicado: (2023)

An empirical model of proton RBE based on the linear correlation between x‐ray and proton radiosensitivity
por: Flint, David B., et al.
Publicado: (2022)

A model for the accurate computation of the lateral scattering of protons in water
por: Bellinzona, EV, et al.
Publicado: (2016)

Dosimetric validation of Monte Carlo and analytical dose engines with raster-scanning $^1$H, $^4$He, $^{12}$C, and $^{16}$O ion-beams using an anthropomorphic phantom
por: Mein, Stewart, et al.
Publicado: (2019)

Monte Carlo-based parametrization of the lateral dose spread for clinical treatment planning of scanned proton and carbon ion beams
por: Parodi, Katia, et al.
Publicado: (2013)

The FLUKA code: An accurate simulation tool for particle therapy
por: Battistoni, Giuseppe, et al.
Publicado: (2016)

Spot-Scanning Hadron Arc (SHArc) Therapy: A Study With Light and Heavy Ions
por: Mein, Stewart, et al.
Publicado: (2021)

Towards Achieving the Full Clinical Potential of Proton Therapy by Inclusion of LET and RBE Models
por: Jones, Bleddyn
Publicado: (2015)

Biologically optimized helium ion plans: calculation approach and its in vitro validation
por: Mairani, A, et al.
Publicado: (2016)

Potential of a Second-Generation Dual-Layer Spectral CT for Dose Calculation in Particle Therapy Treatment Planning
por: Longarino, Friderike K., et al.
Publicado: (2022)

Ways to unravel the clinical potential of carbon ions for head and neck cancer reirradiation: dosimetric comparison and local failure pattern analysis as part of the prospective randomized CARE trial
por: Held, Thomas, et al.
Publicado: (2022)

The impact of proton LET/RBE modeling and robustness analysis on base-of-skull and pediatric craniopharyngioma proton plans relative to VMAT
por: Gutierrez, A., et al.
Publicado: (2019)

Investigating the Implications of a Variable RBE on Proton Dose Fractionation Across a Clinical Pencil Beam Scanned Spread-Out Bragg Peak
por: Marshall, Thomas I., et al.
Publicado: (2016)

The RBE for high-LET radiations with respect to mutagenesis
por: Commission Internationale de Protection contre les Radiations
Publicado: (1972)

RBE for late somatic effects in mice irradiated with 60 MeV protons relative to X-rays
por: Darden, E B, et al.
Publicado: (1971)

Cannot write session to /tmp/vufind_sessions/sess_5i1mor4n19f4sl3po82ji0m0fk