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Effect of Narrow Spectrum Versus Selective Kinase Inhibitors on the Intestinal Proinflammatory Immune Response in Ulcerative Colitis

BACKGROUND: Kinases are key mediators of inflammation, highlighting the potential of kinase inhibitors as treatments for inflammatory disorders. Selective kinase inhibitors, however, have proved disappointing, particularly in the treatment of rheumatoid arthritis and inflammatory bowel disease. Cons...

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Detalles Bibliográficos
Autores principales: Biancheri, Paolo, Foster, Martyn R., Fyfe, Matthew C. T., MacDonald, Thomas T., Sirohi, Sameer, Solanke, Yemisi, Wood, Eleanor, Rowley, Adele, Webber, Steve, Walshe, Claire A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869561/
https://www.ncbi.nlm.nih.gov/pubmed/27104822
http://dx.doi.org/10.1097/MIB.0000000000000759