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Corneal Cross-Linking (with a Partial Deepithelization) in Keratoconus with Five Years of Follow-Up
We performed a retrospective interventional case series including 80 eyes of 48 patients with keratoconus (KC) who were treated with modified corneal cross-linking (CXL) for KC (with a partial deepithelization in a pattern of stripes). The average follow-up was 5.8 years (with a minimum of 5 years)....
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869599/ https://www.ncbi.nlm.nih.gov/pubmed/27199574 http://dx.doi.org/10.4137/OED.S38364 |
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author | Galvis, Virgilio Tello, Alejandro Carreño, Néstor I. Ortiz, Alvaro I. Barrera, Rodrigo Rodriguez, Carlos Julián Ochoa, Miguel E. |
author_facet | Galvis, Virgilio Tello, Alejandro Carreño, Néstor I. Ortiz, Alvaro I. Barrera, Rodrigo Rodriguez, Carlos Julián Ochoa, Miguel E. |
author_sort | Galvis, Virgilio |
collection | PubMed |
description | We performed a retrospective interventional case series including 80 eyes of 48 patients with keratoconus (KC) who were treated with modified corneal cross-linking (CXL) for KC (with a partial deepithelization in a pattern of stripes). The average follow-up was 5.8 years (with a minimum of 5 years). At the last follow-up visit, compared with preoperative values, there were no significant changes in spherical equivalent, average keratometry, corneal thickness, corneal hysteresis, or corneal resistance factor. The distance-corrected visual acuity was 20/39 preoperatively and 20/36 postoperatively (P = 0.3). The endothelial cell count decreased by 4.7% (P < 0.005). These findings suggest that this modified corneal CXL technique is a safe and effective alternative to halt the progression of KC up to five years after the procedure. However, some concerns remain as to whether this technique can affect in some degree the corneal endothelial cells. |
format | Online Article Text |
id | pubmed-4869599 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Libertas Academica |
record_format | MEDLINE/PubMed |
spelling | pubmed-48695992016-05-19 Corneal Cross-Linking (with a Partial Deepithelization) in Keratoconus with Five Years of Follow-Up Galvis, Virgilio Tello, Alejandro Carreño, Néstor I. Ortiz, Alvaro I. Barrera, Rodrigo Rodriguez, Carlos Julián Ochoa, Miguel E. Ophthalmol Eye Dis Original Research We performed a retrospective interventional case series including 80 eyes of 48 patients with keratoconus (KC) who were treated with modified corneal cross-linking (CXL) for KC (with a partial deepithelization in a pattern of stripes). The average follow-up was 5.8 years (with a minimum of 5 years). At the last follow-up visit, compared with preoperative values, there were no significant changes in spherical equivalent, average keratometry, corneal thickness, corneal hysteresis, or corneal resistance factor. The distance-corrected visual acuity was 20/39 preoperatively and 20/36 postoperatively (P = 0.3). The endothelial cell count decreased by 4.7% (P < 0.005). These findings suggest that this modified corneal CXL technique is a safe and effective alternative to halt the progression of KC up to five years after the procedure. However, some concerns remain as to whether this technique can affect in some degree the corneal endothelial cells. Libertas Academica 2016-05-12 /pmc/articles/PMC4869599/ /pubmed/27199574 http://dx.doi.org/10.4137/OED.S38364 Text en © 2016 the author(s), publisher and licensee Libertas Academica Ltd. This is an open-access article distributed under the terms of the Creative Commons CC-BY-NC 3.0 License. |
spellingShingle | Original Research Galvis, Virgilio Tello, Alejandro Carreño, Néstor I. Ortiz, Alvaro I. Barrera, Rodrigo Rodriguez, Carlos Julián Ochoa, Miguel E. Corneal Cross-Linking (with a Partial Deepithelization) in Keratoconus with Five Years of Follow-Up |
title | Corneal Cross-Linking (with a Partial Deepithelization) in Keratoconus with Five Years of Follow-Up |
title_full | Corneal Cross-Linking (with a Partial Deepithelization) in Keratoconus with Five Years of Follow-Up |
title_fullStr | Corneal Cross-Linking (with a Partial Deepithelization) in Keratoconus with Five Years of Follow-Up |
title_full_unstemmed | Corneal Cross-Linking (with a Partial Deepithelization) in Keratoconus with Five Years of Follow-Up |
title_short | Corneal Cross-Linking (with a Partial Deepithelization) in Keratoconus with Five Years of Follow-Up |
title_sort | corneal cross-linking (with a partial deepithelization) in keratoconus with five years of follow-up |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869599/ https://www.ncbi.nlm.nih.gov/pubmed/27199574 http://dx.doi.org/10.4137/OED.S38364 |
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