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Linkage between the Danish National Health Service Prescription Database, the Danish Fetal Medicine Database, and other Danish registries as a tool for the study of drug safety in pregnancy

A linked population-based database is being created in Denmark for research on drug safety during pregnancy. It combines information from the Danish National Health Service Prescription Database (with information on all prescriptions reimbursed in Denmark since 2004), the Danish Fetal Medicine Datab...

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Autores principales: Pedersen, Lars H, Petersen, Olav B, Nørgaard, Mette, Ekelund, Charlotte, Pedersen, Lars, Tabor, Ann, Sørensen, Henrik T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869617/
https://www.ncbi.nlm.nih.gov/pubmed/27274312
http://dx.doi.org/10.2147/CLEP.S98139
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author Pedersen, Lars H
Petersen, Olav B
Nørgaard, Mette
Ekelund, Charlotte
Pedersen, Lars
Tabor, Ann
Sørensen, Henrik T
author_facet Pedersen, Lars H
Petersen, Olav B
Nørgaard, Mette
Ekelund, Charlotte
Pedersen, Lars
Tabor, Ann
Sørensen, Henrik T
author_sort Pedersen, Lars H
collection PubMed
description A linked population-based database is being created in Denmark for research on drug safety during pregnancy. It combines information from the Danish National Health Service Prescription Database (with information on all prescriptions reimbursed in Denmark since 2004), the Danish Fetal Medicine Database, the Danish National Registry of Patients, and the Medical Birth Registry. The new linked database will provide validated information on malformations diagnosed both prenatally and postnatally. The cohort from 2008 to 2014 will comprise 589,000 pregnancies with information on 424,000 pregnancies resulting in live-born children, ∼420,000 pregnancies undergoing prenatal ultrasound scans, 65,000 miscarriages, and 92,000 terminations. It will be updated yearly with information on ∼80,000 pregnancies. The cohort will enable identification of drug exposures associated with severe malformations, not only based on malformations diagnosed after birth but also including those having led to termination of pregnancy or miscarriage. Such combined data will provide a unique source of information for research on the safety of medications used during pregnancy.
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spelling pubmed-48696172016-06-07 Linkage between the Danish National Health Service Prescription Database, the Danish Fetal Medicine Database, and other Danish registries as a tool for the study of drug safety in pregnancy Pedersen, Lars H Petersen, Olav B Nørgaard, Mette Ekelund, Charlotte Pedersen, Lars Tabor, Ann Sørensen, Henrik T Clin Epidemiol Methodology A linked population-based database is being created in Denmark for research on drug safety during pregnancy. It combines information from the Danish National Health Service Prescription Database (with information on all prescriptions reimbursed in Denmark since 2004), the Danish Fetal Medicine Database, the Danish National Registry of Patients, and the Medical Birth Registry. The new linked database will provide validated information on malformations diagnosed both prenatally and postnatally. The cohort from 2008 to 2014 will comprise 589,000 pregnancies with information on 424,000 pregnancies resulting in live-born children, ∼420,000 pregnancies undergoing prenatal ultrasound scans, 65,000 miscarriages, and 92,000 terminations. It will be updated yearly with information on ∼80,000 pregnancies. The cohort will enable identification of drug exposures associated with severe malformations, not only based on malformations diagnosed after birth but also including those having led to termination of pregnancy or miscarriage. Such combined data will provide a unique source of information for research on the safety of medications used during pregnancy. Dove Medical Press 2016-05-11 /pmc/articles/PMC4869617/ /pubmed/27274312 http://dx.doi.org/10.2147/CLEP.S98139 Text en © 2016 Pedersen et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Methodology
Pedersen, Lars H
Petersen, Olav B
Nørgaard, Mette
Ekelund, Charlotte
Pedersen, Lars
Tabor, Ann
Sørensen, Henrik T
Linkage between the Danish National Health Service Prescription Database, the Danish Fetal Medicine Database, and other Danish registries as a tool for the study of drug safety in pregnancy
title Linkage between the Danish National Health Service Prescription Database, the Danish Fetal Medicine Database, and other Danish registries as a tool for the study of drug safety in pregnancy
title_full Linkage between the Danish National Health Service Prescription Database, the Danish Fetal Medicine Database, and other Danish registries as a tool for the study of drug safety in pregnancy
title_fullStr Linkage between the Danish National Health Service Prescription Database, the Danish Fetal Medicine Database, and other Danish registries as a tool for the study of drug safety in pregnancy
title_full_unstemmed Linkage between the Danish National Health Service Prescription Database, the Danish Fetal Medicine Database, and other Danish registries as a tool for the study of drug safety in pregnancy
title_short Linkage between the Danish National Health Service Prescription Database, the Danish Fetal Medicine Database, and other Danish registries as a tool for the study of drug safety in pregnancy
title_sort linkage between the danish national health service prescription database, the danish fetal medicine database, and other danish registries as a tool for the study of drug safety in pregnancy
topic Methodology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869617/
https://www.ncbi.nlm.nih.gov/pubmed/27274312
http://dx.doi.org/10.2147/CLEP.S98139
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