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NOD1/NOD2 signaling links ER stress with inflammation
Endoplasmic reticulum (ER) stress is a major contributor to inflammatory diseases, such as Crohn’s disease and type 2 diabetes(1,2). ER stress induces the unfolded protein response (UPR), which involves activation of three transmembrane receptors, ATF6 (activating transcription factor 6), PERK (prot...
Autores principales: | Keestra-Gounder, A. Marijke, Byndloss, Mariana X., Seyffert, Núbia, Young, Briana M., Chávez-Arroyo, Alfredo, Tsai, April Y., Cevallos, Stephanie A., Winter, Maria G., Pham, Oanh H., Tiffany, Connor R., de Jong, Maarten F., Kerrinnes, Tobias, Ravindran, Resmi, Luciw, Paul A., McSorley, Stephen J., Bäumler, Andreas J., Tsolis, Renée M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869892/ https://www.ncbi.nlm.nih.gov/pubmed/27007849 http://dx.doi.org/10.1038/nature17631 |
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