Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in industrialized countries and is increasing in prevalence. The pathomechanisms, however, are poorly understood. This study assessed the unexpected role of the Hedgehog pathway in adult liver lipid metabolism. Using transgen...

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Detalles Bibliográficos
Autores principales: Matz-Soja, Madlen, Rennert, Christiane, Schönefeld, Kristin, Aleithe, Susanne, Boettger, Jan, Schmidt-Heck, Wolfgang, Weiss, Thomas S, Hovhannisyan, Amalya, Zellmer, Sebastian, Klöting, Nora, Schulz, Angela, Kratzsch, Jürgen, Guthke, Reinhardt, Gebhardt, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869931/
https://www.ncbi.nlm.nih.gov/pubmed/27185526
http://dx.doi.org/10.7554/eLife.13308

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