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Construction of AAV-rat-IL4 and Evaluation of its Modulating Effect on Aβ (1-42)-Induced Proinflammatory Cytokines in Primary Microglia and the B92 Cell Line by Quantitative PCR Assay
BACKGROUND: Interleukin-4 (IL-4), as the most prominent anti-inflammatory cytokine, plays an important role in modulating microglial activation and inflammatory responses in Alzheimer’s disease (AD), a chronic inflammatory disorder. OBJECTIVES: The current study aimed to develop a new recombinant Ad...
Autores principales: | Jamalidoust, Marzieh, Ravanshad, Mehrdad, Namayandeh, Mandana, Zare, Maryam, Asaei, Sadaf, Ziyaeyan, Mazyar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870549/ https://www.ncbi.nlm.nih.gov/pubmed/27217922 http://dx.doi.org/10.5812/jjm.30444 |
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