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Aligned Nanotopography Promotes a Migratory State in Glioblastoma Multiforme Tumor Cells

Glioblastoma multiforme (GBM) is an aggressive, Grade IV astrocytoma with a poor survival rate, primarily due to the GBM tumor cells migrating away from the primary tumor site along the nanotopography of white matter tracts and blood vessels. It is unclear whether this nanotopography influences the...

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Detalles Bibliográficos
Autores principales: Beliveau, Alexander, Thomas, Gawain, Gong, Jiaxin, Wen, Qi, Jain, Anjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870554/
https://www.ncbi.nlm.nih.gov/pubmed/27189099
http://dx.doi.org/10.1038/srep26143