Morc3 mutant mice exhibit reduced cortical area and thickness, accompanied by altered haematopoietic stem cells niche and bone cell differentiation

Morc3, a member of a highly conserved nuclear matrix protein super-family plays an important part in chromatin remodeling, DNA repair, epigenetic regulation and cellular senescence. However, its role in bone homeostasis is not known. In the present study, a phenotype-driven ENU mouse mutagenesis scr...

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Detalles Bibliográficos
Autores principales: Jadhav, Gaurav, Teguh, Dian, Kenny, Jacob, Tickner, Jennifer, Xu, Jiake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870562/
https://www.ncbi.nlm.nih.gov/pubmed/27188231
http://dx.doi.org/10.1038/srep25964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870562/
https://www.ncbi.nlm.nih.gov/pubmed/27188231
http://dx.doi.org/10.1038/srep25964

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