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Integrin CD11b attenuates colitis by strengthening Src-Akt pathway to polarize anti-inflammatory IL-10 expression

Interleukin-10 (IL-10) plays a central role in regulation of intestinal mucosal homeostasis and prevention of inflammatory bowel disease (IBD). We previously reported that CD11b(hi) regulatory dendritic cells (DCs) can produce more IL-10, and CD11b can negatively regulate Toll-like receptors (TLRs)-...

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Detalles Bibliográficos
Autores principales: Hu, Xiang, Han, Chaofeng, Jin, Jing, Qin, Kewei, Zhang, Hua, Li, Tianliang, Li, Nan, Cao, Xuetao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870583/
https://www.ncbi.nlm.nih.gov/pubmed/27188220
http://dx.doi.org/10.1038/srep26252

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