Long-term expression of miRNA for RNA interference using a novel vector system based on a negative-strand RNA virus

RNA interference (RNAi) has emerged as a promising technique for gene therapy. However, the safe and long-term expression of small RNA molecules is a major concern for the application of RNAi therapies in vivo. Borna disease virus (BDV), a non-segmented, negative-strand RNA virus, establishes a pers...

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Detalles Bibliográficos
Autores principales: Honda, Tomoyuki, Yamamoto, Yusuke, Daito, Takuji, Matsumoto, Yusuke, Makino, Akiko, Tomonaga, Keizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870639/
https://www.ncbi.nlm.nih.gov/pubmed/27189575
http://dx.doi.org/10.1038/srep26154

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