Cargando…

Evolutionary origin of the NCSI gene subfamily encoding norcoclaurine synthase is associated with the biosynthesis of benzylisoquinoline alkaloids in plants

Sacred lotus is rich in biologically active compounds, particularly benzylisoquinoline alkaloids (BIAs). Here, we report on isolation of genes encoding (S)-norcoclaurine synthase (NCS) in sacred lotus, which is a key entry-enzyme in BIA biosynthesis. Seven NCS genes, designated NnNCS1 through NnNCS7...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vimolmangkang, Sornkanok, Deng, Xianbao, Owiti, Albert, Meelaph, Thitirat, Ogutu, Collins, Han, Yuepeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870700/ https://www.ncbi.nlm.nih.gov/pubmed/27189519 http://dx.doi.org/10.1038/srep26323

Ejemplares similares

Rational Engineering of (S)-Norcoclaurine Synthase for Efficient Benzylisoquinoline Alkaloids Biosynthesis
por: De Sousa, João P. M., et al.
Publicado: (2023)

Investigation of benzylisoquinoline alkaloid biosynthetic pathway and its transcriptional regulation in lotus
por: Deng, Xianbao, et al.
Publicado: (2018)

Transcriptome Analysis of Stephania tetrandra and Characterization of Norcoclaurine-6-O-Methyltransferase Involved in Benzylisoquinoline Alkaloid Biosynthesis
por: Li, Kunlun, et al.
Publicado: (2022)

Coregulation of Biosynthetic Genes and Transcription Factors for Aporphine-Type Alkaloid Production in Wounded Lotus Provides Insight into the Biosynthetic Pathway of Nuciferine
por: Meelaph, Thitirat, et al.
Publicado: (2018)

Benzylisoquinoline Alkaloids Biosynthesis in Sacred Lotus
por: Menéndez-Perdomo, Ivette M., et al.
Publicado: (2018)

Genes encoding norcoclaurine synthase occur as tandem fusions in the Papaveraceae
por: Li, Jing, et al.
Publicado: (2016)

Molecular characterization of genes encoding leucoanthocyanidin reductase involved in proanthocyanidin biosynthesis in apple
por: Liao, Liao, et al.
Publicado: (2015)

Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase
por: Lichman, Benjamin R., et al.
Publicado: (2017)

Identification and Characterization of Genes Involved in Benzylisoquinoline Alkaloid Biosynthesis in Coptis Species
por: He, Si-Mei, et al.
Publicado: (2018)

De novo biosynthesis of berberine and halogenated benzylisoquinoline alkaloids in Saccharomyces cerevisiae
por: Han, Jianing, et al.
Publicado: (2023)

An apple MYB transcription factor, MdMYB3, is involved in regulation of anthocyanin biosynthesis and flower development
por: Vimolmangkang, Sornkanok, et al.
Publicado: (2013)

Norcoclaurine Synthase: Mechanism of an Enantioselective Pictet-Spengler Catalyzing Enzyme
por: Bonamore, Alessandra, et al.
Publicado: (2010)

Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases
por: Roddan, Rebecca, et al.
Publicado: (2020)

Modulation of benzylisoquinoline alkaloid biosynthesis by overexpression berberine bridge enzyme in Macleaya cordata
por: Huang, Peng, et al.
Publicado: (2018)

Copy number variation of a gene cluster encoding endopolygalacturonase mediates flesh texture and stone adhesion in peach
por: Gu, Chao, et al.
Publicado: (2016)

BIAdb: A curated database of benzylisoquinoline alkaloids
por: Singla, Deepak, et al.
Publicado: (2010)

Green Routes for the Production of Enantiopure Benzylisoquinoline Alkaloids
por: Ghirga, Francesca, et al.
Publicado: (2017)

Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids
por: Vavricka, Christopher J., et al.
Publicado: (2019)

Tyrosine phosphorylation and protein degradation control the transcriptional activity of WRKY involved in benzylisoquinoline alkaloid biosynthesis
por: Yamada, Yasuyuki, et al.
Publicado: (2016)

Modulation of benzylisoquinoline alkaloid biosynthesis by heterologous expression of CjWRKY1 in Eschscholzia californica cells
por: Yamada, Yasuyuki, et al.
Publicado: (2017)

Role of the phloem in the biochemistry and ecophysiology of benzylisoquinoline alkaloid metabolism
por: Lee, Eun-Jeong, et al.
Publicado: (2013)

Molecular Origins of Functional Diversity in Benzylisoquinoline Alkaloid Methyltransferases
por: Morris, Jeremy S., et al.
Publicado: (2019)

Engineering Saccharomyces cerevisiae to produce plant benzylisoquinoline alkaloids
por: Han, Jianing, et al.
Publicado: (2021)

Chromosome-level genome assembly of Aristolochia contorta provides insights into the biosynthesis of benzylisoquinoline alkaloids and aristolochic acids
por: Cui, Xinyun, et al.
Publicado: (2022)

Genome-Wide Profiling of WRKY Genes Involved in Benzylisoquinoline Alkaloid Biosynthesis in California Poppy (Eschscholzia californica)
por: Yamada, Yasuyuki, et al.
Publicado: (2021)

‘Dopamine-first’ mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile
por: Lichman, Benjamin R, et al.
Publicado: (2015)

Author Correction: Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids
por: Vavricka, Christopher J., et al.
Publicado: (2019)

Hairy root induction and benzylisoquinoline alkaloid production in Macleaya cordata
por: Huang, Peng, et al.
Publicado: (2018)

Corrigendum: Molecular Origins of Functional Diversity in Benzylisoquinoline Alkaloid Methyltransferases
por: Morris, Jeremy S., et al.
Publicado: (2019)

Visualization and identification of benzylisoquinoline alkaloids in various nelumbo nucifera tissues
por: Hao, Chenyang, et al.
Publicado: (2023)

Jasmonate-Responsive Transcription Factors NnWRKY70a and NnWRKY70b Positively Regulate Benzylisoquinoline Alkaloid Biosynthesis in Lotus (Nelumbo nucifera)
por: Li, Jing, et al.
Publicado: (2022)

Structural studies of codeinone reductase reveal novel insights into aldo-keto reductase function in benzylisoquinoline alkaloid biosynthesis
por: Carr, Samuel C., et al.
Publicado: (2021)

Biocatalytic Organic Synthesis of Optically Pure (S)-Scoulerine and Berbine and Benzylisoquinoline Alkaloids
por: Schrittwieser, Joerg H., et al.
Publicado: (2011)

Metabolome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants
por: Hagel, Jillian M., et al.
Publicado: (2015)

Transcriptome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants
por: Hagel, Jillian M., et al.
Publicado: (2015)

The chicken gut metagenome and the modulatory effects of plant-derived benzylisoquinoline alkaloids
por: Huang, Peng, et al.
Publicado: (2018)

Benzylisoquinoline Alkaloids from the Stems of Limacia scandens and Their Potential as Autophagy Inhibitors
por: Lee, Hee-Ju, et al.
Publicado: (2022)

Full-length transcriptome and metabolite analysis reveal reticuline epimerase-independent pathways for benzylisoquinoline alkaloids biosynthesis in Sinomenium acutum
por: Yang, Yufan, et al.
Publicado: (2022)

Functional characterization and key residues engineering of a regiopromiscuity O-methyltransferase involved in benzylisoquinoline alkaloid biosynthesis in Nelumbo nucifera
por: Yu, Yuetong, et al.
Publicado: (2022)

Anti-Alzheimer and Antioxidant Effects of Nelumbo nucifera L. Alkaloids, Nuciferine and Norcoclaurine in Alloxan-Induced Diabetic Albino Rats
por: Khan, Shahnaz, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qer8skhk3b32nuuvm3e20k4c67