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Dimethyloxaloylglycine Promotes the Angiogenic Activity of Mesenchymal Stem Cells Derived from iPSCs via Activation of the PI3K/Akt Pathway for Bone Regeneration

The vascularization of tissue-engineered bone is a prerequisite step for the successful repair of bone defects. Hypoxia inducible factor-1α (HIF-1α) plays an essential role in angiogenesis-osteogenesis coupling during bone regeneration and can activate the expression of angiogenic factors in mesench...

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Detalles Bibliográficos
Autores principales: Zhang, Jieyuan, Guan, Junjie, Qi, Xin, Ding, Hao, Yuan, Hong, Xie, Zongping, Chen, Chunyuan, Li, Xiaolin, Zhang, Changqing, Huang, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870708/
https://www.ncbi.nlm.nih.gov/pubmed/27194942
http://dx.doi.org/10.7150/ijbs.14025

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