Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing

BACKGROUND: The presence of histone 3 lysine 9 (H3K9) methylation on the mouse inactive X chromosome has been controversial over the last 15 years, and the functional role of H3K9 methylation in X chromosome inactivation in any species has remained largely unexplored. RESULTS: Here we report the fir...

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Detalles Bibliográficos
Autores principales: Keniry, Andrew, Gearing, Linden J., Jansz, Natasha, Liu, Joy, Holik, Aliaksei Z., Hickey, Peter F., Kinkel, Sarah A., Moore, Darcy L., Breslin, Kelsey, Chen, Kelan, Liu, Ruijie, Phillips, Catherine, Pakusch, Miha, Biben, Christine, Sheridan, Julie M., Kile, Benjamin T., Carmichael, Catherine, Ritchie, Matthew E., Hilton, Douglas J., Blewitt, Marnie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870784/
https://www.ncbi.nlm.nih.gov/pubmed/27195021
http://dx.doi.org/10.1186/s13072-016-0064-6

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