vIL-10-overexpressing human MSCs modulate naïve and activated T lymphocytes following induction of collagenase-induced osteoarthritis

BACKGROUND: Recent efforts in osteoarthritis (OA) research have highlighted synovial inflammation and involvement of immune cells in disease onset and progression. We sought to establish the in-vivo immune response in collagenase-induced OA and investigate the ability of human mesenchymal stem cells...

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Detalles Bibliográficos
Autores principales: Farrell, Eric, Fahy, Niamh, Ryan, Aideen E, Flatharta, Cathal O, O’Flynn, Lisa, Ritter, Thomas, Murphy, J Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870800/
https://www.ncbi.nlm.nih.gov/pubmed/27194025
http://dx.doi.org/10.1186/s13287-016-0331-2

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