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Supplementary motor area deactivation impacts the recovery of hand function from severe peripheral nerve injury
Although some patients have successful peripheral nerve regeneration, a poor recovery of hand function often occurs after peripheral nerve injury. It is believed that the capability of brain plasticity is crucial for the recovery of hand function. The supplementary motor area may play a key role in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870929/ https://www.ncbi.nlm.nih.gov/pubmed/27212933 http://dx.doi.org/10.4103/1673-5374.180756 |
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author | Lu, Ye-chen Liu, Han-qiu Hua, Xu-yun Shen, Yun-dong Xu, Wen-dong Xu, Jian-guang Gu, Yu-dong |
author_facet | Lu, Ye-chen Liu, Han-qiu Hua, Xu-yun Shen, Yun-dong Xu, Wen-dong Xu, Jian-guang Gu, Yu-dong |
author_sort | Lu, Ye-chen |
collection | PubMed |
description | Although some patients have successful peripheral nerve regeneration, a poor recovery of hand function often occurs after peripheral nerve injury. It is believed that the capability of brain plasticity is crucial for the recovery of hand function. The supplementary motor area may play a key role in brain remodeling after peripheral nerve injury. In this study, we explored the activation mode of the supplementary motor area during a motor imagery task. We investigated the plasticity of the central nervous system after brachial plexus injury, using the motor imagery task. Results from functional magnetic resonance imaging showed that after brachial plexus injury, the motor imagery task for the affected limbs of the patients triggered no obvious activation of bilateral supplementary motor areas. This result indicates that it is difficult to excite the supplementary motor areas of brachial plexus injury patients during a motor imagery task, thereby impacting brain remodeling. Deactivation of the supplementary motor area is likely to be a serious problem for brachial plexus injury patients in terms of preparing, initiating and executing certain movements, which may be partly responsible for the unsatisfactory clinical recovery of hand function. |
format | Online Article Text |
id | pubmed-4870929 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-48709292016-05-20 Supplementary motor area deactivation impacts the recovery of hand function from severe peripheral nerve injury Lu, Ye-chen Liu, Han-qiu Hua, Xu-yun Shen, Yun-dong Xu, Wen-dong Xu, Jian-guang Gu, Yu-dong Neural Regen Res Research Article Although some patients have successful peripheral nerve regeneration, a poor recovery of hand function often occurs after peripheral nerve injury. It is believed that the capability of brain plasticity is crucial for the recovery of hand function. The supplementary motor area may play a key role in brain remodeling after peripheral nerve injury. In this study, we explored the activation mode of the supplementary motor area during a motor imagery task. We investigated the plasticity of the central nervous system after brachial plexus injury, using the motor imagery task. Results from functional magnetic resonance imaging showed that after brachial plexus injury, the motor imagery task for the affected limbs of the patients triggered no obvious activation of bilateral supplementary motor areas. This result indicates that it is difficult to excite the supplementary motor areas of brachial plexus injury patients during a motor imagery task, thereby impacting brain remodeling. Deactivation of the supplementary motor area is likely to be a serious problem for brachial plexus injury patients in terms of preparing, initiating and executing certain movements, which may be partly responsible for the unsatisfactory clinical recovery of hand function. Medknow Publications & Media Pvt Ltd 2016-04 /pmc/articles/PMC4870929/ /pubmed/27212933 http://dx.doi.org/10.4103/1673-5374.180756 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Research Article Lu, Ye-chen Liu, Han-qiu Hua, Xu-yun Shen, Yun-dong Xu, Wen-dong Xu, Jian-guang Gu, Yu-dong Supplementary motor area deactivation impacts the recovery of hand function from severe peripheral nerve injury |
title | Supplementary motor area deactivation impacts the recovery of hand function from severe peripheral nerve injury |
title_full | Supplementary motor area deactivation impacts the recovery of hand function from severe peripheral nerve injury |
title_fullStr | Supplementary motor area deactivation impacts the recovery of hand function from severe peripheral nerve injury |
title_full_unstemmed | Supplementary motor area deactivation impacts the recovery of hand function from severe peripheral nerve injury |
title_short | Supplementary motor area deactivation impacts the recovery of hand function from severe peripheral nerve injury |
title_sort | supplementary motor area deactivation impacts the recovery of hand function from severe peripheral nerve injury |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870929/ https://www.ncbi.nlm.nih.gov/pubmed/27212933 http://dx.doi.org/10.4103/1673-5374.180756 |
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