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Intracerebral haemorrhage in Down syndrome: protected or predisposed?

Down syndrome (DS), which arises from trisomy of chromosome 21, is associated with deposition of large amounts of amyloid within the central nervous system. Amyloid accumulates in two compartments: as plaques within the brain parenchyma and in vessel walls of the cerebral microvasculature. The paren...

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Detalles Bibliográficos
Autores principales: Buss, Lewis, Fisher, Elizabeth, Hardy, John, Nizetic, Dean, Groet, Jurgen, Pulford, Laura, Strydom, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870990/
https://www.ncbi.nlm.nih.gov/pubmed/27239286
http://dx.doi.org/10.12688/f1000research.7819.1

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