Cargando…

Intravital imaging reveals new ancillary mechanisms co-opted by cancer cells to drive tumor progression

Intravital imaging is providing new insights into the dynamics of tumor progression in native tissues and has started to reveal the layers of complexity found in cancer. Recent advances in intravital imaging have allowed us to look deeper into cancer behavior and to dissect the interactions between...

Descripción completa

Detalles Bibliográficos
Autores principales: Vennin, Claire, Herrmann, David, Lucas, Morghan C., Timpson, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870995/
https://www.ncbi.nlm.nih.gov/pubmed/27239290
http://dx.doi.org/10.12688/f1000research.8090.1
Descripción
Sumario:Intravital imaging is providing new insights into the dynamics of tumor progression in native tissues and has started to reveal the layers of complexity found in cancer. Recent advances in intravital imaging have allowed us to look deeper into cancer behavior and to dissect the interactions between tumor cells and the ancillary host niche that promote cancer development. In this review, we provide an insight into the latest advances in cancer biology achieved by intravital imaging, focusing on recently discovered mechanisms by which tumor cells manipulate normal tissue to facilitate disease progression.