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Temperature feedback-controlled photothermal treatment with diffusing applicator: theoretical and experimental evaluations

To minimize thermal injury, the current study evaluated the real-time temperature monitoring with a proportional-integrative-derivative (PID) controller during 980-nm photothermal treatment with a radially-diffusing applicator. Both simulations and experiments demonstrated comparable thermal behavio...

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Detalles Bibliográficos
Autores principales: Nguyen, Trung Hau, Park, Suhyun, Hlaing, Kyu Kyu, Kang, Hyun Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871092/
https://www.ncbi.nlm.nih.gov/pubmed/27231632
http://dx.doi.org/10.1364/BOE.7.001932
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author Nguyen, Trung Hau
Park, Suhyun
Hlaing, Kyu Kyu
Kang, Hyun Wook
author_facet Nguyen, Trung Hau
Park, Suhyun
Hlaing, Kyu Kyu
Kang, Hyun Wook
author_sort Nguyen, Trung Hau
collection PubMed
description To minimize thermal injury, the current study evaluated the real-time temperature monitoring with a proportional-integrative-derivative (PID) controller during 980-nm photothermal treatment with a radially-diffusing applicator. Both simulations and experiments demonstrated comparable thermal behaviors in temperature distribution and the degree of irreversible tissue denaturation. The PID-controlled application constantly maintained the pre-determined temperature of 353 K (steady-state error = < 1 K). Due to constant energy delivery, coagulation volumes linearly increased up to 1.04 ± 0.02 cm(3) with irradiation time. Integration of temperature feedback with diffuser-assisted photothermal treatments can provide a feasible therapeutic modality to treat pancreatic tumors in an effective manner.
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spelling pubmed-48710922016-05-26 Temperature feedback-controlled photothermal treatment with diffusing applicator: theoretical and experimental evaluations Nguyen, Trung Hau Park, Suhyun Hlaing, Kyu Kyu Kang, Hyun Wook Biomed Opt Express Article To minimize thermal injury, the current study evaluated the real-time temperature monitoring with a proportional-integrative-derivative (PID) controller during 980-nm photothermal treatment with a radially-diffusing applicator. Both simulations and experiments demonstrated comparable thermal behaviors in temperature distribution and the degree of irreversible tissue denaturation. The PID-controlled application constantly maintained the pre-determined temperature of 353 K (steady-state error = < 1 K). Due to constant energy delivery, coagulation volumes linearly increased up to 1.04 ± 0.02 cm(3) with irradiation time. Integration of temperature feedback with diffuser-assisted photothermal treatments can provide a feasible therapeutic modality to treat pancreatic tumors in an effective manner. Optical Society of America 2016-04-19 /pmc/articles/PMC4871092/ /pubmed/27231632 http://dx.doi.org/10.1364/BOE.7.001932 Text en © 2016 Optical Society of America
spellingShingle Article
Nguyen, Trung Hau
Park, Suhyun
Hlaing, Kyu Kyu
Kang, Hyun Wook
Temperature feedback-controlled photothermal treatment with diffusing applicator: theoretical and experimental evaluations
title Temperature feedback-controlled photothermal treatment with diffusing applicator: theoretical and experimental evaluations
title_full Temperature feedback-controlled photothermal treatment with diffusing applicator: theoretical and experimental evaluations
title_fullStr Temperature feedback-controlled photothermal treatment with diffusing applicator: theoretical and experimental evaluations
title_full_unstemmed Temperature feedback-controlled photothermal treatment with diffusing applicator: theoretical and experimental evaluations
title_short Temperature feedback-controlled photothermal treatment with diffusing applicator: theoretical and experimental evaluations
title_sort temperature feedback-controlled photothermal treatment with diffusing applicator: theoretical and experimental evaluations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871092/
https://www.ncbi.nlm.nih.gov/pubmed/27231632
http://dx.doi.org/10.1364/BOE.7.001932
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