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Accommodating volume-constant age-dependent optical (AVOCADO) model of the crystalline GRIN lens

The purpose of this manuscript is to introduce a new age-dependent model of the human lens with two GRIN power distributions (axial and radial) that allow decoupling of its refractive power and axial optical path length. The aspect ratio of the lens core can be held constant under accommodation, as...

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Autores principales: Sheil, Conor J., Goncharov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871097/
https://www.ncbi.nlm.nih.gov/pubmed/27231637
http://dx.doi.org/10.1364/BOE.7.001985
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author Sheil, Conor J.
Goncharov, Alexander V.
author_facet Sheil, Conor J.
Goncharov, Alexander V.
author_sort Sheil, Conor J.
collection PubMed
description The purpose of this manuscript is to introduce a new age-dependent model of the human lens with two GRIN power distributions (axial and radial) that allow decoupling of its refractive power and axial optical path length. The aspect ratio of the lens core can be held constant under accommodation, as well as the lens volume by varying the asphericity of the lens external surfaces. The spherical aberration calculated by exact raytracing is shown to be in line with experimental data. The proposed model is compared to previous GRIN models from the literature, and it is concluded that the features of the new model will be useful for GRIN reconstruction in future experimental studies; in particular, studies of the accommodation-dependent properties of the ageing human eye. A proposed logarithmic model of the lens core enables decoupling of three fundamental optical characteristics of the lens, namely axial optical path length, optical power and third-order spherical aberration, without changing the external shape of the lens. Conversely, the near-surface GRIN structure conforms to the external shape of the lens, which is necessary for accommodation modelling.
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spelling pubmed-48710972016-05-26 Accommodating volume-constant age-dependent optical (AVOCADO) model of the crystalline GRIN lens Sheil, Conor J. Goncharov, Alexander V. Biomed Opt Express Article The purpose of this manuscript is to introduce a new age-dependent model of the human lens with two GRIN power distributions (axial and radial) that allow decoupling of its refractive power and axial optical path length. The aspect ratio of the lens core can be held constant under accommodation, as well as the lens volume by varying the asphericity of the lens external surfaces. The spherical aberration calculated by exact raytracing is shown to be in line with experimental data. The proposed model is compared to previous GRIN models from the literature, and it is concluded that the features of the new model will be useful for GRIN reconstruction in future experimental studies; in particular, studies of the accommodation-dependent properties of the ageing human eye. A proposed logarithmic model of the lens core enables decoupling of three fundamental optical characteristics of the lens, namely axial optical path length, optical power and third-order spherical aberration, without changing the external shape of the lens. Conversely, the near-surface GRIN structure conforms to the external shape of the lens, which is necessary for accommodation modelling. Optical Society of America 2016-04-22 /pmc/articles/PMC4871097/ /pubmed/27231637 http://dx.doi.org/10.1364/BOE.7.001985 Text en © 2016 Optical Society of America
spellingShingle Article
Sheil, Conor J.
Goncharov, Alexander V.
Accommodating volume-constant age-dependent optical (AVOCADO) model of the crystalline GRIN lens
title Accommodating volume-constant age-dependent optical (AVOCADO) model of the crystalline GRIN lens
title_full Accommodating volume-constant age-dependent optical (AVOCADO) model of the crystalline GRIN lens
title_fullStr Accommodating volume-constant age-dependent optical (AVOCADO) model of the crystalline GRIN lens
title_full_unstemmed Accommodating volume-constant age-dependent optical (AVOCADO) model of the crystalline GRIN lens
title_short Accommodating volume-constant age-dependent optical (AVOCADO) model of the crystalline GRIN lens
title_sort accommodating volume-constant age-dependent optical (avocado) model of the crystalline grin lens
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871097/
https://www.ncbi.nlm.nih.gov/pubmed/27231637
http://dx.doi.org/10.1364/BOE.7.001985
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