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Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement

Compromised endothelial barrier function is a hallmark of inflammation. Rho family GTPases are critical in regulating endothelial barrier function, yet their precise roles, particularly in sphingosine-1-phosphate (S1P)-induced endothelial barrier enhancement, remain elusive. Confluent cultures of hu...

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Detalles Bibliográficos
Autores principales:	Zhang, Xun E., Adderley, Shaquria P., Breslin, Jerome W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871357/ https://www.ncbi.nlm.nih.gov/pubmed/27187066 http://dx.doi.org/10.1371/journal.pone.0155490

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