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Impact of Genetic Polymorphism of methylenetetrahydrofolate reductase C677T on Development of Hyperhomocysteinemia and Related Oxidative Changes in Egyptian β-Thalassemia Major Patients

BACKGROUND: β-thalasemia major (β-TM) patients often suffer from various vascular complications together with increased oxidative stress. Hyperhomocysteinemia (Hhcy) has been defined as a risk factor for these complications. Genetic polymorphism of methylenetetrahydrofolate reductase (MTHFR) C677T h...

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Detalles Bibliográficos
Autores principales: Abd-Elmawla, Mai A., Rizk, Sherine M., Youssry, Ilham, Shaheen, Amira A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871363/
https://www.ncbi.nlm.nih.gov/pubmed/27187171
http://dx.doi.org/10.1371/journal.pone.0155070