TGF-β Small Molecule Inhibitor SB431542 Reduces Rotator Cuff Muscle Fibrosis and Fatty Infiltration By Promoting Fibro/Adipogenic Progenitor Apoptosis

Rotator cuff tears represent a large burden of muscle-tendon injuries in our aging population. While small tears can be repaired surgically with good outcomes, critical size tears are marked by muscle atrophy, fibrosis, and fatty infiltration, which can lead to failed repair, frequent re-injury, and...

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Detalles Bibliográficos
Autores principales: Davies, Michael R., Liu, Xuhui, Lee, Lawrence, Laron, Dominique, Ning, Anne Y., Kim, Hubert T., Feeley, Brian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871364/
https://www.ncbi.nlm.nih.gov/pubmed/27186977
http://dx.doi.org/10.1371/journal.pone.0155486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871364/
https://www.ncbi.nlm.nih.gov/pubmed/27186977
http://dx.doi.org/10.1371/journal.pone.0155486

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