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Tgif1 and Tgif2 Regulate Axial Patterning in Mouse

Tgif1 and Tgif2 are transcriptional repressors that inhibit the transcriptional response to transforming growth factor β signaling, and can repress gene expression by direct binding to DNA. Loss of function mutations in TGIF1 are associated with holoprosencephaly (HPE) in humans. In mice, embryos la...

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Detalles Bibliográficos
Autores principales:	Melhuish, Tiffany A., Taniguchi, Kenichiro, Wotton, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871493/ https://www.ncbi.nlm.nih.gov/pubmed/27187787 http://dx.doi.org/10.1371/journal.pone.0155837

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