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Three-Dimensional Reconstruction of the Bony Nasolacrimal Canal by Automated Segmentation of Computed Tomography Images

OBJECTIVE: To apply a fully automated method to quantify the 3D structure of the bony nasolacrimal canal (NLC) from CT scans whereby the size and main morphometric characteristics of the canal can be determined. DESIGN: Cross-sectional study. SUBJECTS: 36 eyes of 18 healthy individuals. METHODS: Usi...

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Autores principales: Jañez-Garcia, Lucia, Saenz-Frances, Federico, Ramirez-Sebastian, Jose M., Toledano-Fernandez, Nicolas, Urbasos-Pascual, Maria, Jañez-Escalada, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871497/
https://www.ncbi.nlm.nih.gov/pubmed/27187800
http://dx.doi.org/10.1371/journal.pone.0155436
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author Jañez-Garcia, Lucia
Saenz-Frances, Federico
Ramirez-Sebastian, Jose M.
Toledano-Fernandez, Nicolas
Urbasos-Pascual, Maria
Jañez-Escalada, Luis
author_facet Jañez-Garcia, Lucia
Saenz-Frances, Federico
Ramirez-Sebastian, Jose M.
Toledano-Fernandez, Nicolas
Urbasos-Pascual, Maria
Jañez-Escalada, Luis
author_sort Jañez-Garcia, Lucia
collection PubMed
description OBJECTIVE: To apply a fully automated method to quantify the 3D structure of the bony nasolacrimal canal (NLC) from CT scans whereby the size and main morphometric characteristics of the canal can be determined. DESIGN: Cross-sectional study. SUBJECTS: 36 eyes of 18 healthy individuals. METHODS: Using software designed to detect the boundaries of the NLC on CT images, 36 NLC reconstructions were prepared. These reconstructions were then used to calculate NLC volume. The NLC axis in each case was determined according to a polygonal model and to 2(nd), 3(rd) and 4(th) degree polynomials. From these models, NLC sectional areas and length were determined. For each variable, descriptive statistics and normality tests (Kolmogorov-Smirnov and Shapiro-Wilk) were established. MAIN OUTCOME MEASURES: Time for segmentation, NLC volume, axis, sectional areas and length. RESULTS: Mean processing time was around 30 seconds for segmenting each canal. All the variables generated were normally distributed. Measurements obtained using the four models polygonal, 2(nd), 3(rd) and 4(th) degree polynomial, respectively, were: mean canal length 14.74, 14.3, 14.80, and 15.03 mm; mean sectional area 15.15, 11.77, 11.43, and 11.56 mm(2); minimum sectional area 8.69, 7.62, 7.40, and 7.19 mm(2); and mean depth of minimum sectional area (craniocaudal) 7.85, 7.71, 8.19, and 8.08 mm. CONCLUSION: The method proposed automatically reconstructs the NLC on CT scans. Using these reconstructions, morphometric measurements can be calculated from NLC axis estimates based on polygonal and 2(nd), 3(rd) and 4(th) polynomial models.
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spelling pubmed-48714972016-05-31 Three-Dimensional Reconstruction of the Bony Nasolacrimal Canal by Automated Segmentation of Computed Tomography Images Jañez-Garcia, Lucia Saenz-Frances, Federico Ramirez-Sebastian, Jose M. Toledano-Fernandez, Nicolas Urbasos-Pascual, Maria Jañez-Escalada, Luis PLoS One Research Article OBJECTIVE: To apply a fully automated method to quantify the 3D structure of the bony nasolacrimal canal (NLC) from CT scans whereby the size and main morphometric characteristics of the canal can be determined. DESIGN: Cross-sectional study. SUBJECTS: 36 eyes of 18 healthy individuals. METHODS: Using software designed to detect the boundaries of the NLC on CT images, 36 NLC reconstructions were prepared. These reconstructions were then used to calculate NLC volume. The NLC axis in each case was determined according to a polygonal model and to 2(nd), 3(rd) and 4(th) degree polynomials. From these models, NLC sectional areas and length were determined. For each variable, descriptive statistics and normality tests (Kolmogorov-Smirnov and Shapiro-Wilk) were established. MAIN OUTCOME MEASURES: Time for segmentation, NLC volume, axis, sectional areas and length. RESULTS: Mean processing time was around 30 seconds for segmenting each canal. All the variables generated were normally distributed. Measurements obtained using the four models polygonal, 2(nd), 3(rd) and 4(th) degree polynomial, respectively, were: mean canal length 14.74, 14.3, 14.80, and 15.03 mm; mean sectional area 15.15, 11.77, 11.43, and 11.56 mm(2); minimum sectional area 8.69, 7.62, 7.40, and 7.19 mm(2); and mean depth of minimum sectional area (craniocaudal) 7.85, 7.71, 8.19, and 8.08 mm. CONCLUSION: The method proposed automatically reconstructs the NLC on CT scans. Using these reconstructions, morphometric measurements can be calculated from NLC axis estimates based on polygonal and 2(nd), 3(rd) and 4(th) polynomial models. Public Library of Science 2016-05-17 /pmc/articles/PMC4871497/ /pubmed/27187800 http://dx.doi.org/10.1371/journal.pone.0155436 Text en © 2016 Jañez-Garcia et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Jañez-Garcia, Lucia
Saenz-Frances, Federico
Ramirez-Sebastian, Jose M.
Toledano-Fernandez, Nicolas
Urbasos-Pascual, Maria
Jañez-Escalada, Luis
Three-Dimensional Reconstruction of the Bony Nasolacrimal Canal by Automated Segmentation of Computed Tomography Images
title Three-Dimensional Reconstruction of the Bony Nasolacrimal Canal by Automated Segmentation of Computed Tomography Images
title_full Three-Dimensional Reconstruction of the Bony Nasolacrimal Canal by Automated Segmentation of Computed Tomography Images
title_fullStr Three-Dimensional Reconstruction of the Bony Nasolacrimal Canal by Automated Segmentation of Computed Tomography Images
title_full_unstemmed Three-Dimensional Reconstruction of the Bony Nasolacrimal Canal by Automated Segmentation of Computed Tomography Images
title_short Three-Dimensional Reconstruction of the Bony Nasolacrimal Canal by Automated Segmentation of Computed Tomography Images
title_sort three-dimensional reconstruction of the bony nasolacrimal canal by automated segmentation of computed tomography images
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871497/
https://www.ncbi.nlm.nih.gov/pubmed/27187800
http://dx.doi.org/10.1371/journal.pone.0155436
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