Drug-Based Lead Discovery: The Novel Ablative Antiretroviral Profile of Deferiprone in HIV-1-Infected Cells and in HIV-Infected Treatment-Naive Subjects of a Double-Blind, Placebo-Controlled, Randomized Exploratory Trial

Antiretrovirals suppress HIV-1 production yet spare the sites of HIV-1 production, the HIV-1 DNA-harboring cells that evade immune detection and enable viral resistance on-drug and viral rebound off-drug. Therapeutic ablation of pathogenic cells markedly improves the outcome of many diseases. We ext...

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Detalles Bibliográficos
Autores principales: Saxena, Deepti, Spino, Michael, Tricta, Fernando, Connelly, John, Cracchiolo, Bernadette M., Hanauske, Axel-Rainer, D’Alliessi Gandolfi, Darlene, Mathews, Michael B., Karn, Jonathan, Holland, Bart, Park, Myung Hee, Pe’ery, Tsafi, Palumbo, Paul E., Hanauske-Abel, Hartmut M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871512/
https://www.ncbi.nlm.nih.gov/pubmed/27191165
http://dx.doi.org/10.1371/journal.pone.0154842

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