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Cysteine Peptidase B Regulates Leishmania mexicana Virulence through the Modulation of GP63 Expression

Cysteine peptidases play a central role in the biology of Leishmania. In this work, we sought to further elucidate the mechanism(s) by which the cysteine peptidase CPB contributes to L. mexicana virulence and whether CPB participates in the formation of large communal parasitophorous vacuoles induce...

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Detalles Bibliográficos
Autores principales: Casgrain, Pierre-André, Martel, Caroline, McMaster, W. Robert, Mottram, Jeremy C., Olivier, Martin, Descoteaux, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871588/
https://www.ncbi.nlm.nih.gov/pubmed/27191844
http://dx.doi.org/10.1371/journal.ppat.1005658

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