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Cysteine Peptidase B Regulates Leishmania mexicana Virulence through the Modulation of GP63 Expression
Cysteine peptidases play a central role in the biology of Leishmania. In this work, we sought to further elucidate the mechanism(s) by which the cysteine peptidase CPB contributes to L. mexicana virulence and whether CPB participates in the formation of large communal parasitophorous vacuoles induce...
Autores principales: | Casgrain, Pierre-André, Martel, Caroline, McMaster, W. Robert, Mottram, Jeremy C., Olivier, Martin, Descoteaux, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871588/ https://www.ncbi.nlm.nih.gov/pubmed/27191844 http://dx.doi.org/10.1371/journal.ppat.1005658 |
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