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Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABA(A) receptors on dendritic spines

Adolescent synaptic pruning is thought to enable optimal cognition because it is disrupted in certain neuropathologies, yet the initiator of this process is unknown. One factor not yet considered is the α4βδ GABA(A) receptor (GABAR), an extrasynaptic inhibitory receptor which first emerges on dendri...

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Detalles Bibliográficos
Autores principales:	Afroz, Sonia, Parato, Julie, Shen, Hui, Smith, Sheryl Sue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871702/ https://www.ncbi.nlm.nih.gov/pubmed/27136678 http://dx.doi.org/10.7554/eLife.15106

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