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A Systematic Comparison Identifies an ATP-Based Viability Assay as Most Suitable Read-Out for Drug Screening in Glioma Stem-Like Cells

Serum-free culture methods for patient-derived primary glioma cultures, selecting for glioma stem-like cells (GSCs), are becoming the gold standard in neurooncology research. These GSCs can be implemented in drug screens to detect patient-specific responses, potentially bridging the translational ga...

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Detalles Bibliográficos
Autores principales: Kleijn, A., Kloezeman, J. J., Balvers, R. K., van der Kaaij, M., Dirven, C. M. F., Leenstra, S., Lamfers, M. L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871979/
https://www.ncbi.nlm.nih.gov/pubmed/27274737
http://dx.doi.org/10.1155/2016/5623235